2580935-57-3
2580935-57-3
Chemical Structure
PTPN22-IN-1
- CAS No.: 2580935-57-3
- Formula:C26H21N3O5
- Molecular Weight:455.46
IUPAC Name: (S)-6-(2-([1,1'-biphenyl]-4-carboxamido)propanamido)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: PBKUVBJIDJIKJJ-HNNXBMFYSA-N
SMILES: O=C1C2=CC(NC([C@H](C)NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=O)=CC=C2NC=C1C(O)=O
Biological Activity: PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 µM; Ki=0.50 µM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses[1]. From WO2021007491A1 compound L-1.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PTPN22-IN-1 | 99.60% | PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 µM; Ki=0.50 µM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses. From WO2021007491A1 compound L-1. | ||||||||||||||||||||
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