2583719-08-6
2583719-08-6
Chemical Structure
TyK2-IN-21-d3
- CAS No.: 2583719-08-6
- Formula:C21H22D3N8O7P
- Molecular Weight:535.46
InChIKey: LPGOZJVRCODLIY-UWRQEQCTSA-N
SMILES: O=P(O)(OCN1C=C(C(NC([2H])([2H])[2H])=O)C(NC2=CC=CC(C3=NN(C)N=N3)=C2OC)=C/C1=N\C(C4CC4)=O)O
Biological Activity: TyK2-IN-21-d3 (Compound 3c) is the orally active prodrug of the tyrosine kinase 2. TyK2-IN-21-d3 exhibits good chemical stability in aqueous system under different pHs. TyK2-IN-21-d3 alleviates the effect of gastric acid changes on drug absorption and improve the drug bioavailability in rat model[1].
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TyK2-IN-21-d3 | TyK2-IN-21-d3 (Compound 3c) is the orally active prodrug of the tyrosine kinase 2. TyK2-IN-21-d3 exhibits good chemical stability in aqueous system under different pHs. TyK2-IN-21-d3 alleviates the effect of gastric acid changes on drug absorption and improve the drug bioavailability in rat model. | |||||||||||||||||||||
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