2585015-90-1
2585015-90-1
Chemical Structure
YM-I-26
- CAS No.: 2585015-90-1
- Formula:C28H33ClN2O5S2
- Molecular Weight:577.16
InChIKey: CVYOPZKUUYJUHO-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(CCN(CC2=C(OCCC)C=CC(Cl)=C2)C(CC3=CSC=C3)=O)C=C1)(N4CCOCC4)=O
Biological Activity: YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse microglial BV2 cells and inhibits the production of IL-1β and IL-10. YM-I-26 can be used to study the immunomodulatory activity associated with inflammation[1].
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YM-I-26 | YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse microglial BV2 cells and inhibits the production of IL-1β and IL-10. YM-I-26 can be used to study the immunomodulatory activity associated with inflammation. | |||||||||||||||||||||
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