2588211-44-1
2588211-44-1
Chemical Structure
Topoisomerase I inhibitor 2
- CAS No.: 2588211-44-1
- Formula:C18H15NO3
- Molecular Weight:293.32
IUPAC Name: 9,10-dimethoxy-6H-chromeno[3,4-b]quinoline
InChIKey: UUDRXJXFLKSENM-UHFFFAOYSA-N
SMILES: COC1=C(C=C2N=C3COC4=C(C3=CC2=C1)C=CC=C4)OC
Biological Activity: Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect[1].
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Topoisomerase I inhibitor 2 | Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect. | |||||||||||||||||||||
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