26145-48-2
26145-48-2
Chemical Structure
Phyllomedusin
- CAS No.: 26145-48-2
- Formula:C52H82N16O13S
- Molecular Weight:1171.37
InChIKey: GGIXGYYACCFXOQ-GUXVTFBTSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)[C@H](CC(N)=O)NC([C@@H](N3)CCC3=O)=O
Biological Activity: Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus[1][2][3].
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Phyllomedusin | Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus. | |||||||||||||||||||||
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References
- [1]. Ganjiwale AD, et al. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. [Content Brief]
- [2]. Bertaccini G, et al. Effect of substance P and its natural analogues on gastric emptying of the conscious rat. Br J Pharmacol. 1981 Feb;72(2):221-3. [Content Brief]
- [3]. Bertaccini G, et al. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. [Content Brief]
