2619512-84-2
2619512-84-2
Chemical Structure
Lenalidomide-acetylene-Br
- CAS No.: 2619512-84-2
- Formula:C17H15BrN2O3
- Molecular Weight:375.22
InChIKey: ZILZKVZXYARDOJ-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=C(C2)C(C#CCCBr)=CC=C3)=O)=O
Biological Activity: Lenalidomide-acetylene-Br is a PROTAC Linker taht makes up HJM-561 (HY-156698). HJM-561 is a potent, selective, and orally active EGFR PROTAC to inhiibit Osimertinib (HY-15772)-resistant EGFR triple mutations.
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Lenalidomide-acetylene-Br | Lenalidomide-acetylene-Br is a PROTAC Linker taht makes up HJM-561 (HY-156698). HJM-561 is a potent, selective, and orally active EGFR PROTAC to inhiibit Osimertinib (HY-15772)-resistant EGFR triple mutations. | |||||||||||||||||||||
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