2624336-88-3
2624336-88-3
Chemical Structure
Lenalidomide 4'-PEG2-amine dihydrochloride
- CAS No.: 2624336-88-3
- Formula:C19H28Cl2N4O5
- Molecular Weight:463.36
InChIKey: RFRZCOFHURLZLN-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCOCCN)=CC=C3)=O)=O.Cl.Cl
Biological Activity: Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lenalidomide 4'-PEG2-amine dihydrochloride | 98.78% | Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Pomalidomide-PEG3-C2-NH2 | Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. | |||||||||||||||||||||
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Pomalidomide-PEG3-C2-NH2 hydrochloride | 96.64% | Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. | ||||||||||||||||||||
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Thalidomide-PEG2-C2-NH2 | Thalidomide-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. | |||||||||||||||||||||
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Thalidomide-PEG2-C2-NH2 hydrochloride | 99.93% | Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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Lenalidomide 4'-PEG1-amine dihydrochloride | 99.51% | Lenalidomide 4'-PEG1-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG1-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Lenalidomide 4'-PEG3-amine dihydrochloride | 98.97% | Lenalidomide 4'-PEG3-amine dihydrochloride is a lenalidomide (HY-A0003)-derived immunomodulator and monofunctional synthetic intermediate, as well as a E3 ubiquitin ligase ligand. Lenalidomide 4'-PEG3-amine dihydrochloride can be used for the preparation of small-molecule drug conjugates and heterobifunctional protein degraders. | ||||||||||||||||||||
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Lenalidomide 4'-PEG1-azide | Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.. | |||||||||||||||||||||
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Lenalidomide 4'-PEG2-azide | 98.2% | Lenalidomide 4'-PEG2-azide is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-azide can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Lenalidomide-COCH-PEG2-azido | Lenalidomide-COCH-PEG2-azido is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based cereblon ligand and a linker. Lenalidomide-COCH-PEG2-azido can be used in the synthesis of PROTAC AKR1C3 degrader-1 (HY-163609). | |||||||||||||||||||||
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Pomalidomide-PEG3-OH | Pomalidomide-PEG3-OH (compound 53b) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. | |||||||||||||||||||||
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