26250-84-0
Chemical Structure
Boc-Pip-OH
Synonym(s): Boc-L-pipecolic acid
- CAS No.: 26250-84-0
- Formula:C11H19NO4
- Molecular Weight:229.28
IUPAC Name: (S)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid
InChIKey: JQAOHGMPAAWWQO-QMMMGPOBSA-N
SMILES: [C@@H]1(N(C(OC(C)(C)C)=O)CCCC1)C(=O)O
Biological Activity: Boc-Pip-OH (Boc-L-pipecolic acid) is a t-butyloxycarbonylamino acid. Boc-Pip-OH can serve as a radical precursor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Boc-Pip-OH | 98.81% | Boc-Pip-OH (Boc-L-pipecolic acid) is a t-butyloxycarbonylamino acid. Boc-Pip-OH can serve as a radical precursor. | ||||||||||||||||||||
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Boc-Pro-OMe | 98.86% | Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body. | ||||||||||||||||||||
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(R)-1-(tert-Butoxycarbonyl)-2-methylpiperidine-2-carboxylic acid | 99.19% | (R)-1-(tert-Butoxycarbonyl)-2-methylpiperidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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(2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid | 98.0% | N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Boc-Hyp-OH | 99.57% | Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs | ||||||||||||||||||||
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N-Boc-cis-4-hydroxy-L-proline | 97.0% | N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2 | ||||||||||||||||||||
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N-Boc-cis-4-Hydroxy-D-proline | 98.0% | N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs. | ||||||||||||||||||||
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Boc-D-HoPro-OH | 98.0% | Boc-D-HoPro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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(4S)-1-Boc-4-amino-D-proline | 95.0% | (4S)-1-Boc-4-amino-D-proline is an amino acid derivative that can be used for compound synthesis. | ||||||||||||||||||||
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N-Boc-trans-4-fluoro-L-proline | 98.0% | N-Boc-trans-4-fluoro-L-proline is a non-natural amino acid substitute used to construct monoclonal antibodies that specifically target the seed conformation of tau protein. | ||||||||||||||||||||
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Boc-Pyr-OtBu | Boc-Pyr-OtBu (Boc-L-Pyroglutamicacidtert-butylester) is a peptide intermediate and can be used in peptide synthesis. | |||||||||||||||||||||
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References
- [1]. Chen S, et al. Visible-Light-Induced Cascade Difunctionalization of Indoles Enabled by the Synergy of Photoredox and Photoexcited Ketones: Direct Access to Alkylated Pyrrolophenanthridones. Org Lett. 2022 Dec 30;24(51):9386-9391. [Content Brief]
- [2]. Perseo G, et al. Preparation and analytical data of some unusual t-butyloxycarbonyl-amino acids. Int J Pept Protein Res. 1983 Mar;21(3):227-30. [Content Brief]