2629192-96-5
2629192-96-5
Chemical Structure
LRRK2/NUAK1/TYK2-IN-1
- CAS No.: 2629192-96-5
- Formula:C20H11F3N6
- Molecular Weight:392.34
IUPAC Name: 5-(2,6-difluorophenyl)-9-fluoro-8-(pyridazin-4-yl)-2,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine
InChIKey: VMEVFMJJHNJSPX-UHFFFAOYSA-N
SMILES: FC1=CC=CC(F)=C1C2=NC3=C(C4=NNC=C4N2)C=C(F)C(C5=CC=NN=C5)=C3
Biological Activity: LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].
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LRRK2/NUAK1/TYK2-IN-1 | LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research. | |||||||||||||||||||||
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