2630904-44-6

(S)-Navlimetostat Chemical Structure
2630904-44-6

Chemical Structure

(S)-Navlimetostat

Synonym(s): (S)-MRTX-1719;(S)-BMS-986504

  • CAS No.: 2630904-44-6
  • Formula:C23H18ClFN6O2
  • Molecular Weight:464.88

IUPAC Name: 2-(4-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile

InChIKey: BZKIOORWZAXIBA-UHFFFAOYSA-N

SMILES: FC1=C(C=C(C(C#N)=[C@@]1[C@@]2=C(C3=CC=C4C(C(CN)=NNC4=O)=C3)C=NN2C)OC5CC5)Cl

Biological Activity: (S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-139611B
(S)-Navlimetostat 98.15% (S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References