2632259-92-6

ZW4864 free base Chemical Structure
2632259-92-6

Chemical Structure

ZW4864 free base

  • CAS No.: 2632259-92-6
  • Formula:C33H42N6O3
  • Molecular Weight:570.72

IUPAC Name: (R)-N-(4-(1H-pyrazol-4-yl)benzyl)-N-cyclopropyl-1-(3-((2-methyl-1-oxo-1-(piperazin-1-yl)propan-2-yl)oxy)phenyl)piperidine-3-carboxamide

InChIKey: DEGJSKLSOCKWSF-AREMUKBSSA-N

SMILES: O=C([C@H]1CN(C2=CC=CC(OC(C)(C)C(N3CCNCC3)=O)=C2)CCC1)N(C4CC4)CC5=CC=C(C6=CNN=C6)C=C5

Biological Activity: ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-132300A
ZW4864 free base 98.71% ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References