2633013-75-7
2633013-75-7
Chemical Structure
PDIC-NC
- CAS No.: 2633013-75-7
- Formula:C32H26Cl6N4O4
- Molecular Weight:743.29
InChIKey: FFFBAHMNWCSWIN-UHFFFAOYSA-N
SMILES: O=C1C2=CC(Cl)=C3C4=C(C=C5C(N(CCN(C)C)C(C6=CC(Cl)=C(C4=C56)C7=C3C2=C(C(N1CCN(C)C)=O)C=C7Cl)=O)=O)Cl.Cl.Cl
Biological Activity: PDIC-NC is a STING agonist. PDIC-NC is cytotoxic to tumor cells and induces ROS explosion, apoptosis and autophagy. PDIC-NC has lung specific distribution and can be used in the study of lung cancer[1][2].
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PDIC-NC | PDIC-NC is a STING agonist. PDIC-NC is cytotoxic to tumor cells and induces ROS explosion, apoptosis and autophagy. PDIC-NC has lung specific distribution and can be used in the study of lung cancer. | |||||||||||||||||||||
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References
- [1]. Liu Z, et al. Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angew Chem Int Ed Engl. 2021 Jul 12;60(29):16215-16223. [Content Brief]
- [2]. Zhao X, et al. Sulfonated Perylene as Three-in-One STING Agonist for Cancer Chemo-Immunotherapy. Angew Chem Int Ed Engl. 2024 Mar 11;63(11):e202318799. [Content Brief]
