2637949-91-6

XL44 Chemical Structure
2637949-91-6

Chemical Structure

XL44

  • CAS No.: 2637949-91-6
  • Formula:C23H17FN2O3
  • Molecular Weight:388.39

InChIKey: UOTAUCCFVUPGRQ-NDENLUEZSA-N

SMILES: O=C(C1=CC=C(OC)C=C1)NC2=CC=CC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2

Biological Activity: XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins[1].

Cat. No. Product Name Purity Description Pricing
HY-162393
XL44 99.76% XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References