2638512-56-6
2638512-56-6
Chemical Structure
(S,R,S)-AHPC-Me-10-bromodecanoic acid
- CAS No.: 2638512-56-6
- Formula:C33H49BrN4O4S
- Molecular Weight:677.74
InChIKey: ABDLPHQFLKRDFO-ZMOHVDKYSA-N
SMILES: O=C([C@@H](NC(CCCCCCCCCBr)=O)C(C)(C)C)N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C=C2)C3=C(N=CS3)C)C)=O
Biological Activity: (S,R,S)-AHPC-Me-10-bromodecanoic acid is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand 2 (HY-112078) and linker 10-bromoheptanoic acid. (S,R,S)-AHPC-Me-10-bromodecanoic acid can be used for synthesis of PROTAC PI3Kδ degrader-1 (HY-176239)[1].
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(S,R,S)-AHPC-Me-10-bromodecanoic acid | (S,R,S)-AHPC-Me-10-bromodecanoic acid is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand 2 (HY-112078) and linker 10-bromoheptanoic acid. (S,R,S)-AHPC-Me-10-bromodecanoic acid can be used for synthesis of PROTAC PI3Kδ degrader-1 (HY-176239). | |||||||||||||||||||||
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