2639474-65-8
2639474-65-8
Chemical Structure
Dazukibart
Synonym(s): PF-06823859
- CAS No.: 2639474-65-8
- Formula:N/A
- Molecular Weight:(145.36 kDa)
SMILES: [Dazukibart]
Biological Activity: Dazukibart (PF‑06823859) is a humanized IgG1 monoclonal antibody targeting IFN‑β that binds to and neutralizes IFN-β. Dazukibart can be used in research on autoimmune inflammatory diseases such as dermatomyositis[1][2].
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Dazukibart | 99.9% | Dazukibart (PF‑06823859) is a humanized IgG1 monoclonal antibody targeting IFN‑β that binds to and neutralizes IFN-β. Dazukibart can be used in research on autoimmune inflammatory diseases such as dermatomyositis. | ||||||||||||||||||||
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References
- [1]. Sevim E, et al. A comprehensive review of dermatomyositis treatments - from rediscovered classics to promising horizons. Expert review of clinical immunology. 2024 Feb;20(2):197-209.
- [2]. Kaewin S, et al. Inhibition of the type I interferon receptor pathway protects against muscle weakness induced by dermatomyositis serum. Annals of the rheumatic diseases. 2026 Jun;85(6):1180-1190. [Content Brief]
