2639835-02-0
2639835-02-0
Chemical Structure
DHODH-IN-20
- CAS No.: 2639835-02-0
- Formula:C24H25F4N3O3
- Molecular Weight:479.47
IUPAC Name: (S)-5-fluoro-4-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-imidazol-4-yl)-N-(o-tolyl)-2-((1,1,1-trifluoropropan-2-yl)oxy)benzamide
InChIKey: JGGJFEOIKVIQJV-AWEZNQCLSA-N
SMILES: O=C(NC1=CC=CC=C1C)C2=CC(F)=C(C3=CN(C)C(C(C)(O)C)=N3)C=C2O[C@@H](C)C(F)(F)F
Biological Activity: DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia[1].
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DHODH-IN-20 | DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia. | |||||||||||||||||||||
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