2640543-21-9
Chemical Structure
Tropolone-3-tetrahydrofuran
- CAS No.: 2640543-21-9
- Formula:C11H12O3
- Molecular Weight:192.21
IUPAC Name: 2-hydroxy-3-(tetrahydrofuran-2-yl)cyclohepta-2,4,6-trien-1-one
InChIKey: SSSAEIGHFDCWMF-UHFFFAOYSA-N
SMILES: O=C1C=CC=CC(=C1O)C2OCCC2
Biological Activity: Tropolone-3-tetrahydrofuran (example 40) is a Tropolone derivative that modulates liposomal Fe (III) efflux and increases iron uptake in DMT1-deficient cells. Tropolone-3-tetrahydrofuran modulates metabolic networks by targeting transporters such as DMT1 and FPN1, thereby alleviating iron malabsorption and restoring systemic iron homeostasis. Tropolone-3-tetrahydrofuran can be used in research on iron dysregulation-related diseases such as anemia, hemochromatosis, and neurodegenerative diseases[1].
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Tropolone-3-tetrahydrofuran | Tropolone-3-tetrahydrofuran (example 40) is a Tropolone derivative that modulates liposomal Fe (III) efflux and increases iron uptake in DMT1-deficient cells. Tropolone-3-tetrahydrofuran modulates metabolic networks by targeting transporters such as DMT1 and FPN1, thereby alleviating iron malabsorption and restoring systemic iron homeostasis. Tropolone-3-tetrahydrofuran can be used in research on iron dysregulation-related diseases such as anemia, hemochromatosis, and neurodegenerative diseases. | |||||||||||||||||||||
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