264618-44-2
264618-44-2
Chemical Structure
SSR 146977
- CAS No.: 264618-44-2
- Formula:C35H42Cl2N4O2
- Molecular Weight:621.64
IUPAC Name: (R)-3-(1-(3-(1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl)propyl)-4-phenylpiperidin-4-yl)-1,1-dimethylurea
InChIKey: XWPBINGFFFZAOZ-UMSFTDKQSA-N
SMILES: O=C(N(C)C)NC1(CCN(CC1)CCC[C@]2(CN(CCC2)C(C3=CC=CC=C3)=O)C4=CC=C(C(Cl)=C4)Cl)C5=CC=CC=C5
Biological Activity: SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SSR 146977 | SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
