2648838-76-8
Chemical Structure
Pan-RAF kinase inhibitor 1
- CAS No.: 2648838-76-8
- Formula:C26H24F3N3O4
- Molecular Weight:499.48
IUPAC Name: N-(3-(2-((1R,5S)-3-oxabicyclo[3.1.0]hexan-1-yl)-6-(2-hydroxyethoxy)pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide
InChIKey: RCDIRDLSBIPQBX-IQGLISFBSA-N
SMILES: OCCOC1=NC([C@]23[C@](COC3)([H])C2)=CC(C4=CC(NC(C5=CC=NC(C(F)(F)F)=C5)=O)=CC=C4C)=C1
Biological Activity: Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B)[1].
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Pan-RAF kinase inhibitor 1 | Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B). | |||||||||||||||||||||
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