2648855-18-7
2648855-18-7
Chemical Structure
RK-701
- CAS No.: 2648855-18-7
- Formula:C26H30N4O3
- Molecular Weight:446.54
IUPAC Name: (S)-N-(1-((4-cyanophenyl)amino)-4-cyclopropyl-1-oxobutan-2-yl)-3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxamide
InChIKey: OWORSODZTADOQX-IBGZPJMESA-N
SMILES: CC1=C(C(N[C@@H](CCC2CC2)C(NC3=CC=C(C=C3)C#N)=O)=O)NC(CC(C)(C4)C)=C1C4=O
Biological Activity: RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC50 value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RK-701 | 98.01% | RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC50 value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A. | ||||||||||||||||||||
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