2649154-82-3
2649154-82-3
Chemical Structure
CIAC001
- CAS No.: 2649154-82-3
- Formula:C20H25N3O2
- Molecular Weight:339.43
InChIKey: AGJUGOFAIPQXTD-MWSTZMHHSA-N
SMILES: CC(N1N=CC=N1)C2=CC(O)=C(C(O)=C2)[C@@H]3C=C(CC[C@H]3C(C)=C)C
Biological Activity: CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CIAC001 | 99.70% | CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
