2649727-40-0
2649727-40-0
Chemical Structure
DC10SMe
- CAS No.: 2649727-40-0
- Formula:C35H29N5O4S2
- Molecular Weight:647.77
IUPAC Name: 5-(3-(methyldisulfanyl)propanamido)-N-(2-((9aS)-4-oxo-2,4,9,9a-tetrahydro-1H-benzo[e]cyclopropa[c]indole-2-carbonyl)-1H-indol-5-yl)-1H-indole-2-carboxamide
InChIKey: LMJIHUHQBTUVRR-HPUOVZDUSA-N
SMILES: O=C(C1=CC2=C(C=CC(NC(CCSSC)=O)=C2)N1)NC3=CC4=C(C=C3)NC(C(N5C(C67[C@H](C7)C5)=CC(C8=C6C=CC=C8)=O)=O)=C4
Biological Activity: DC10SMe is a DNA alkylator, can be used in the synthesis of antibody-drug conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively[1].
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DC10SMe | DC10SMe is a DNA alkylator, can be used in the synthesis of antibody-drug conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively. | |||||||||||||||||||||
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