2650546-39-5
2650546-39-5
Chemical Structure
WNY1613
- CAS No.: 2650546-39-5
- Formula:C29H35N9O3
- Molecular Weight:557.65
IUPAC Name: 4-(cyclobutanecarbonyl)-1-((2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-2-one
InChIKey: ZGZMQKJLWFWWDG-UHFFFAOYSA-N
SMILES: O=C1N(CC2=NC3=C(N4CCOCC4)N=C(N5C6=CC=CC=C6N=C5CC)N=C3N2C)CCN(C(C7CCC7)=O)C1
Biological Activity: WNY1613 is a potent and selective PI3Kδ inhibitor with piperazinone-containing purine scaffold. WNY1613 induces cancer cell apoptosis and inhibits the phosphorylation of PI3K downstream components in NHL cell lines. WNY1613 exhibits anti-NHL activity in vitro and in vivo[1].
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WNY1613 | WNY1613 is a potent and selective PI3Kδ inhibitor with piperazinone-containing purine scaffold. WNY1613 induces cancer cell apoptosis and inhibits the phosphorylation of PI3K downstream components in NHL cell lines. WNY1613 exhibits anti-NHL activity in vitro and in vivo. | |||||||||||||||||||||
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