26530-26-7
26530-26-7
Chemical Structure
KM04416
- CAS No.: 26530-26-7
- Formula:C12H11NO3S
- Molecular Weight:249.29
IUPAC Name: ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
InChIKey: BZBRYBISKLKJCA-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=CC=C(N2SC=CC2=O)C=C1
Biological Activity: KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KM04416 | 98.76% | KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation. | ||||||||||||||||||||
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References
- [1]. Sehyun Oh, et al. Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression. Theranostics. 2023 Jan 1;13(2):438-457. [Content Brief]
- [2]. Gurmit Singh, et al. Mitochondrial FAD-linked Glycerol-3-phosphate Dehydrogenase: A Target for Cancer Therapeutics. Pharmaceuticals (Basel). 2014 Feb 11;7(2):192-206. [Content Brief]
