2653338-75-9
2653338-75-9
Chemical Structure
PROTAC EZH2 Degrader-39
- CAS No.: 2653338-75-9
- Formula:C59H77N7O8
- Molecular Weight:1012.28
InChIKey: YVJALPMAXFAUEB-UHFFFAOYSA-N
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)CCCCCCCCCCCCOC5=C(C6=CC=C5)C(N(C6=O)C7CCC(NC7=O)=O)=O)=CC(C(NCC8=C(C=C(NC8=O)C)C)=O)=C2C
Biological Activity: PROTAC EZH2 Degrader-39 (compound 18) is a PROTAC protein degrader targeting EZH2 with a target IC50 of 61.00 nM. PROTAC EZH2 Degrader-39 functionally inhibits EZH2 methyltransferase activity[1].
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PROTAC EZH2 Degrader-39 | PROTAC EZH2 Degrader-39 (compound 18) is a PROTAC protein degrader targeting EZH2 with a target IC50 of 61.00 nM. PROTAC EZH2 Degrader-39 functionally inhibits EZH2 methyltransferase activity. | |||||||||||||||||||||
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