2653349-51-8
2653349-51-8
Chemical Structure
S16–1029
- CAS No.: 2653349-51-8
- Formula:C23H25N7O3
- Molecular Weight:447.49
InChIKey: GPJOTHGHTFYDBV-UHFFFAOYSA-N
SMILES: O=C(CN1C(C2=NON=C2N)=NC3=C1C=CC=C3)NC4=CC=C(CCN5CCOCC5)C=C4
Biological Activity: S16–1029 is a selective and orally active butyrylcholinesterase (BChE) inhibitor with IC50s of 11.35 nM and 48.1 nM for eqBChE and hBChE, respectively. S16–1029 could cross the blood-brain barrier (BBB) and reach the central nervous system (CNS). S16–1029 can be used for Alzheimer's disease (AD) research[1].
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S16–1029 | S16–1029 is a selective and orally active butyrylcholinesterase (BChE) inhibitor with IC50s of 11.35 nM and 48.1 nM for eqBChE and hBChE, respectively. S16–1029 could cross the blood-brain barrier (BBB) and reach the central nervous system (CNS). S16–1029 can be used for Alzheimer's disease (AD) research. | |||||||||||||||||||||
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