2653350-02-6
2653350-02-6
Chemical Structure
PF-1010
- CAS No.: 2653350-02-6
- Formula:C34H27ClF3N3O6
- Molecular Weight:666.04
InChIKey: WRTVIEQREAULIL-SSEXGKCCSA-N
SMILES: N#CC(C=C1)=CC=C1COC(C=C(C(Cl)=C2)NCC3=C(C(C4=CC=C(C=C4)OC(F)(F)F)=CC=C3)C)=C2CN5[C@H](COC5=O)C(O)=O
Biological Activity: PF-1010 is a CD73 inhibitor with an IC50 ranging from 101 to 1000 nM. PF-1010 blocks the interaction between CD73 protein and its substrate, and inhibits the enzymatic activity of CD73. PF-1010 is applicable to the research of cancer, infectious diseases, autoimmune diseases and neurodegenerative diseases[1].
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PF-1010 | PF-1010 is a CD73 inhibitor with an IC50 ranging from 101 to 1000 nM. PF-1010 blocks the interaction between CD73 protein and its substrate, and inhibits the enzymatic activity of CD73. PF-1010 is applicable to the research of cancer, infectious diseases, autoimmune diseases and neurodegenerative diseases. | |||||||||||||||||||||
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