2669070-40-8
2669070-40-8
Chemical Structure
BuChE-IN-1
- CAS No.: 2669070-40-8
- Formula:C23H23FN2O4S
- Molecular Weight:442.50
IUPAC Name: N-((2-((4-fluorophenoxy)methyl)thiazol-4-yl)methyl)-N-isobutylbenzo[d][1,3]dioxole-5-carboxamide
InChIKey: HFRZJOXEZTXXPW-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(OCO2)C2=C1)N(CC3=CSC(COC4=CC=C(F)C=C4)=N3)CC(C)C
Biological Activity: BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE). Butyrylcholinesterase (BuChE) is recently regarded as a biomarker in progressed Alzheimer’s disease (AD). BuChE-IN-1 shows low cytotoxicity and high blood brain barrier (BBB) permeability. BuChE-IN-1 is a promising BuChE inhibitor for the research of AD[1].
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BuChE-IN-1 | BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE). Butyrylcholinesterase (BuChE) is recently regarded as a biomarker in progressed Alzheimer’s disease (AD). BuChE-IN-1 shows low cytotoxicity and high blood brain barrier (BBB) permeability. BuChE-IN-1 is a promising BuChE inhibitor for the research of AD. | |||||||||||||||||||||
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