2670430-25-6
Chemical Structure
Antibacterial agent 328
- CAS No.: 2670430-25-6
- Formula:C18H12BrF3N4O
- Molecular Weight:437.21
InChIKey: SCBJVPJGGJSUKU-NUGSKGIGSA-N
SMILES: O=C(N/N=C/C1=CC=C(N2N=CC(Br)=C2)C=C1)C3=CC=C(C(F)(F)F)C=C3
Biological Activity: Antibacterial agent 328 is a enoyl-ACP reductase (InhA) inhibitor and antimycobacterial agent. Antibacterial agent 328 blocks mycolic acid biosynthesis in Mycobacterium tuberculosis. Antibacterial agent 328 acts on both drug-resistant and drug-susceptible Mycobacterium tuberculosis strains. Antibacterial agent 328 exhibits favorable pharmacokinetic properties, drug-likeness, and a safety-related selectivity index. Antibacterial agent 328 can be used for research on tuberculosis[1].
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Antibacterial agent 328 | Antibacterial agent 328 is a enoyl-ACP reductase (InhA) inhibitor and antimycobacterial agent. Antibacterial agent 328 blocks mycolic acid biosynthesis in Mycobacterium tuberculosis. Antibacterial agent 328 acts on both drug-resistant and drug-susceptible Mycobacterium tuberculosis strains. Antibacterial agent 328 exhibits favorable pharmacokinetic properties, drug-likeness, and a safety-related selectivity index. Antibacterial agent 328 can be used for research on tuberculosis. | |||||||||||||||||||||
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