2676211-62-2
2676211-62-2
Chemical Structure
PROTAC BRD9 Degrader-6
- CAS No.: 2676211-62-2
- Formula:C47H56N8O6
- Molecular Weight:829.00
InChIKey: OBNRBCUHEAAFPS-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=CC(OC)=C(CN4CCC(CC4)CN5CCC6(CC5)CN(C6)C7=CC=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=C7)C(OC)=C3)=CN1C)C=C(N%10CCC%10)N=C2
Biological Activity: PROTAC BRD9 Degrader-6 (Compound D1) is a racemic PROTAC degrader that recruits cereblon to induce targeted degradation of BRD9. PROTAC BRD9 Degrader-6 has an IC50 of 0.13 nM in SYO-1 cells. It can be used in research on BAF complex-related diseases, such as cancer, infections and synovial sarcoma[1].
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PROTAC BRD9 Degrader-6 | 98.19% | PROTAC BRD9 Degrader-6 (Compound D1) is a racemic PROTAC degrader that recruits cereblon to induce targeted degradation of BRD9. PROTAC BRD9 Degrader-6 has an IC50 of 0.13 nM in SYO-1 cells. It can be used in research on BAF complex-related diseases, such as cancer, infections and synovial sarcoma. | ||||||||||||||||||||
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