26763-19-9
Chemical Structure
Polyadenylic acid potassium
Synonym(s): Poly(A)
- CAS No.: 26763-19-9
- Formula:N/A
- Molecular Weight:267KDa (Approximately)
IUPAC Name: potassium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen phosphate
SMILES: NC1=C2C(N([C@@H]3O[C@H](COP(O)(O[K])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[n]
Biological Activity: Polyadenylic acid potassium (Poly(A)) is a polyribonucleotide. Polyadenylic acid potassium constitutes the 3'-poly(A) tail of eukaryotic mRNAs, governing mRNA maturation, stability, and translation initiation. Polyadenylic acid potassium serves as a target for studying nucleic acid structure-function relationships, with small molecules binding its tail influencing mRNA function and protein production. Polyadenylic acid (potassium) can be used for the research of cancer[1][2].
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Polyadenylic acid potassium | 90.00% | Polyadenylic acid potassium (Poly(A)) is a polyribonucleotide. Polyadenylic acid potassium constitutes the 3'-poly(A) tail of eukaryotic mRNAs, governing mRNA maturation, stability, and translation initiation. Polyadenylic acid potassium serves as a target for studying nucleic acid structure-function relationships, with small molecules binding its tail influencing mRNA function and protein production. Polyadenylic acid (potassium) can be used for the research of cancer. | ||||||||||||||||||||
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References
- [1]. Giri P, et al. Molecular aspects of small molecules-poly(A) interaction: an approach to RNA based drug design. Curr Med Chem. 2009;16(8):965-987. [Content Brief]
- [2]. Cuomo F, et al. Polyadenylic acid binding on cationic liposomes doped with the non-ionic nucleolipid Lauroyl Uridine. Colloids Surf B Biointerfaces. 2011;82(2):277-282. [Content Brief]
