2677830-11-2
2677830-11-2
Chemical Structure
HOTN
- CAS No.: 2677830-11-2
- Formula:C39H40Br2N2O
- Molecular Weight:712.56
InChIKey: DVYPIZWTGFWWMQ-UHFFFAOYSA-M
SMILES: C[N+](C)(CCC[N+]1=CC=C(C=C1)/C=C/C2=CC=C(C=C2)/C(C3=CC=CC=C3)=C(C4=CC=C(C=C4)O)\C5=CC=CC=C5)C.[Br-].[Br-]
Biological Activity: HOTN is a hypochlorous acid (HClO) Fluorescent indicator. HOTN is oxidized by HClO, causing cleavage of its Py+-N+ moiety and a change in hydrophobicity, which in turn triggers aggregation-induced emission to generate a strong fluorescent signal. HOTN is used for in vivo imaging of inflammation and hepatocellular carcinoma, as these diseases typically result in high levels of HClO[1].
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HOTN | HOTN is a hypochlorous acid (HClO) Fluorescent indicator. HOTN is oxidized by HClO, causing cleavage of its Py+-N+ moiety and a change in hydrophobicity, which in turn triggers aggregation-induced emission to generate a strong fluorescent signal. HOTN is used for in vivo imaging of inflammation and hepatocellular carcinoma, as these diseases typically result in high levels of HClO. | |||||||||||||||||||||
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