2682889-57-0
2682889-57-0
Chemical Structure
RIPK1-IN-9
- CAS No.: 2682889-57-0
- Formula:C26H25FN6O2
- Molecular Weight:472.51
IUPAC Name: 3-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-6-(2-(cyclopentyloxy)-5-fluorobenzyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one
InChIKey: NFZIVWWKQSSLRB-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CC(C3=CC4=NC(N)=NN4C=C3)=C2)CCN1CC5=CC(F)=CC=C5OC6CCCC6
Biological Activity: RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM)[1].
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RIPK1-IN-9 | RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM). | |||||||||||||||||||||
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