268545-87-5
268545-87-5
Chemical Structure
NBI-34041
Synonym(s): SB-723620
- CAS No.: 268545-87-5
- Formula:C22H26Cl2N4
- Molecular Weight:417.37
IUPAC Name: 1-(2,4-dichlorophenyl)-5-(heptan-4-yl)-7-methyl-4,5-dihydro-3H-2,2a,5,8-tetraazaacenaphthylene
InChIKey: AKLMUGFDGONMAA-UHFFFAOYSA-N
SMILES: CC1=NC2=C3C(N(C(CCC)CCC)CCN3N=C2C4=CC=C(Cl)C=C4Cl)=C1
Biological Activity: NBI-34041 (SB-723620) is a selective and orally active nonpeptide CRF1 receptor antagonist with an IC50 of 58.9 nM and a Ki of 4.0 nM for human CRF1 receptor. NBI-34041 has no inhibitory effect on the CRF2 receptor. NBI-34041 can be used for depression and anxiety disorders research.
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NBI-34041 | NBI-34041 (SB-723620) is a selective and orally active nonpeptide CRF1 receptor antagonist with an IC50 of 58.9 nM and a Ki of 4.0 nM for human CRF1 receptor. NBI-34041 has no inhibitory effect on the CRF2 receptor. NBI-34041 can be used for depression and anxiety disorders research. | |||||||||||||||||||||
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