2685739-28-8
2685739-28-8
Chemical Structure
ZG-2033
- CAS No.: 2685739-28-8
- Formula:C15H14N2O2S
- Molecular Weight:286.35
IUPAC Name: N-(3,5-dimethoxyphenyl)benzo[d]isothiazol-3-amine
InChIKey: VITJWQGYLIMHDA-UHFFFAOYSA-N
SMILES: COC1=CC(OC)=CC(NC2=NSC3=CC=CC=C23)=C1
Biological Activity: ZG-2033 (Compound 26) is an orally active HIF-2α agonist that demonstrates nanomolar activity in luciferase reporter gene assays (EC50 = 490 nM). ZG-2033 has the effect of alleviating anemia and exhibits synergistic action with AKB-6548 (HY-101277) in anemia, and can be used in the study of renal anemia[1].
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ZG-2033 | ZG-2033 (Compound 26) is an orally active HIF-2α agonist that demonstrates nanomolar activity in luciferase reporter gene assays (EC50 = 490 nM). ZG-2033 has the effect of alleviating anemia and exhibits synergistic action with AKB-6548 (HY-101277) in anemia, and can be used in the study of renal anemia. | |||||||||||||||||||||
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