2699604-50-5
Chemical Structure
HPK1-IN-29
- CAS No.: 2699604-50-5
- Formula:C26H18F3N5O2
- Molecular Weight:489.45
IUPAC Name: 4-(4-((5-oxa-7-azaspiro[2.5]oct-6-en-6-yl)amino)-2,6-difluorophenoxy)-3-(4-fluorophenyl)-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
InChIKey: QSCRZQWKTHMGCG-UHFFFAOYSA-N
SMILES: N#CC1=CN=C2NC=C(C2=C1OC3=C(C=C(NC4=NCC5(CC5)CO4)C=C3F)F)C6=CC=C(F)C=C6
Biological Activity: HPK1-IN-29 is a potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 enhances the body's anti-tumor immunity. HPK1-IN-29 has the potential for the research of immune-related diseases, especially tumor (extracted from patent WO2021175270A1, compound 38)[1].
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HPK1-IN-29 | HPK1-IN-29 is a potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 enhances the body's anti-tumor immunity. HPK1-IN-29 has the potential for the research of immune-related diseases, especially tumor (extracted from patent WO2021175270A1, compound 38). | |||||||||||||||||||||
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