2705226-66-8
2705226-66-8
Chemical Structure
13,14-Dihydro PGE1-d4
Synonym(s): 13,14-Dihydroprostaglandin E1-d4; PGE0-d4
- CAS No.: 2705226-66-8
- Formula:C20H32D4O5
- Molecular Weight:360.52
SMILES: CCCCC[C@@H](CC[C@@H]([C@@H](CC1=O)O)[C@H]1CCCC([2H])(C([2H])(CC(O)=O)[2H])[2H])O
Biological Activity: 13,14-Dihydro PGE1-d4 (13,14-Dihydroprostaglandin E1-d4) is deuterium labeled 13,14-Dihydro PGE1. 13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
13,14-Dihydro PGE1-d4 | 13,14-Dihydro PGE1-d4 (13,14-Dihydroprostaglandin E1-d4) is deuterium labeled 13,14-Dihydro PGE1. 13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
13,14-Dihydro PGE1 | 13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Katzenschlager R, et al. Synergism between PGE1-metabolites(13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation. Prostaglandins Leukot Essent Fatty Acids. 1992 Mar;45(3):207-10. [Content Brief]
