2708274-72-8
2708274-72-8
Chemical Structure
PMO-G
- CAS No.: 2708274-72-8
- Formula:C43H46ClN8O7P
- Molecular Weight:853.30
InChIKey: WAHZVPMCAUKPIH-BZIXDFOGSA-N
SMILES: CN(C)P(OC[C@H](C1)O[C@@H](N2C3=NC(NC(C(C)C)=O)=NC(OCCC4=CC=C(C=C4)[N+]([O-])=O)=C3N=C2)CN1C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(Cl)=O
Biological Activity: PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy[1][2].
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PMO-G | PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy. | |||||||||||||||||||||
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References
- [1]. An, J. Y., et al., (2020). Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy. Nanoscale research letters, 15(1), 133. [Content Brief]
- [2]. Lin, C., et al., (2020). Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle. Molecular therapy : the journal of the American Society of Gene Therapy, 28(5), 1339–1358. [Content Brief]
