2712741-60-9
2712741-60-9
Chemical Structure
Abdenoflast
- CAS No.: 2712741-60-9
- Formula:C23H27N3O4S
- Molecular Weight:441.55
IUPAC Name: N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,6,7,8-tetrahydro-5,8-ethanofuro[3,2-c]azepine-2-sulfonamide
InChIKey: LQKIQSJLXCYGOX-UHFFFAOYSA-N
SMILES: O=C(NC=1C2=C(C=C3C1CCC3)CCC2)NS(=O)(=O)C=4OC5=C(C4)CN6CCC5CC6
Biological Activity: Abdenoflast (Compound 12) is an NLRP3 modulator with an IL-1β inhibitory IC50 < 1 μM in human whole blood[1].
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Abdenoflast | Abdenoflast (Compound 12) is an NLRP3 modulator with an IL-1β inhibitory IC50 < 1 μM in human whole blood. | |||||||||||||||||||||
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