2714434-41-8
2714434-41-8
Chemical Structure
YAP/TAZ-TEAD-IN-3
- CAS No.: 2714434-41-8
- Formula:C24H21ClF2N2O3
- Molecular Weight:458.88
InChIKey: RUJIOLXLDFOAMK-MCFWBGNESA-N
SMILES: O=C(C1=[C@@]([C@@]2=C3[C@H](C)[C@](C4=CC=CC=C4)(CN)OC3=CC(F)=C2Cl)C(F)=C(OC)C=C1)N
Biological Activity: YAP/TAZ-TEAD-IN-3 is a YAP/TAZ-TEAD interaction inhibitor with an IC50 of 1.8 nM. YAP/TAZ-TEAD-IN-3 can be used as a TEAD1 ligand to construct PROTACs, such as PROTAC TEAD degrader-2 (HY-186021)[1].
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YAP/TAZ-TEAD-IN-3 | YAP/TAZ-TEAD-IN-3 is a YAP/TAZ-TEAD interaction inhibitor with an IC50 of 1.8 nM. YAP/TAZ-TEAD-IN-3 can be used as a TEAD1 ligand to construct PROTACs, such as PROTAC TEAD degrader-2 (HY-186021). | |||||||||||||||||||||
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