2721484-76-8
2721484-76-8
Chemical Structure
Anti-inflammatory agent 22
- CAS No.: 2721484-76-8
- Formula:C22H16O6
- Molecular Weight:376.36
IUPAC Name: (E)-2-(3-(3,4-dihydroxyphenyl)acryloyl)-5-hydroxyphenyl benzoate
InChIKey: SOPVGBOKHBQLRO-UXBLZVDNSA-N
SMILES: O=C(C1=C(C=C(C=C1)O)OC(C2=CC=CC=C2)=O)/C=C/C3=CC=C(C(O)=C3)O
Biological Activity: Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice[1].
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Anti-inflammatory agent 22 | Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice. | |||||||||||||||||||||
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