2727084-00-4
2727084-00-4
Chemical Structure
CXF-009
- CAS No.: 2727084-00-4
- Formula:C33H38N8O5
- Molecular Weight:626.71
InChIKey: ROJGUOQTMJJWMJ-UHFFFAOYSA-N
SMILES: O=C(NC1=C(NC2=NC=C3C(N(CCCN4CCN(CC4)C(C=C)=O)C(N(C3)C5=CC(OC)=CC(OC)=C5)=O)=N2)C=CC=C1)C=C
Biological Activity: CXF-009 is a selective and covalent FGFR4 inhibitor, with the IC50 of 48 nM. CXF-009 targeting Cys477 and Cys552 of FGFR4, and can be used for the study of hepatocellular carcinoma[1].
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CXF-009 | CXF-009 is a selective and covalent FGFR4 inhibitor, with the IC50 of 48 nM. CXF-009 targeting Cys477 and Cys552 of FGFR4, and can be used for the study of hepatocellular carcinoma. | |||||||||||||||||||||
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