2734910-37-1
2734910-37-1
Chemical Structure
DEG-35
- CAS No.: 2734910-37-1
- Formula:C25H21N3O5
- Molecular Weight:443.45
SMILES: COC1=CC2=C(C=C(C=C2)C(NC3=CC4=C(C(N(C4)C5CCC(NC5=O)=O)=O)C=C3)=O)C=C1
Biological Activity: DEG-35 is a CRBN-dependent, dual IKZF2 and CK1α molecule glue degrader, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. DEG-35 activates the p53 apoptosis pathway. DEG-35 can be used in the research for Acute Myeloid Leukemia (AML)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DEG-35 | 98.88% | DEG-35 is a CRBN-dependent, dual IKZF2 and CK1α molecule glue degrader, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. DEG-35 activates the p53 apoptosis pathway. DEG-35 can be used in the research for Acute Myeloid Leukemia (AML). | ||||||||||||||||||||
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