2735015-60-6

TTBK1-IN-1 Chemical Structure
2735015-60-6

Chemical Structure

TTBK1-IN-1

  • CAS No.: 2735015-60-6
  • Formula:C18H19N5O2
  • Molecular Weight:337.38

IUPAC Name: (S)-1-(1-(2-amino-6-methoxypyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-3-methylpent-1-yn-3-ol

InChIKey: HPJVZSVEIGCFJP-SFHVURJKSA-N

SMILES: O[C@@](C)(CC)C#CC1=CC2=C(C=CN2C3=CC(OC)=NC(N)=N3)C=N1

Biological Activity: TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimer’s disease and related tauopathies[1]. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No. Product Name Purity Description Pricing
HY-134968
TTBK1-IN-1 99.17% TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimer’s disease and related tauopathies. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References