2738392-83-9

SOS1-IN-4 Chemical Structure
2738392-83-9

Chemical Structure

SOS1-IN-4

  • CAS No.: 2738392-83-9
  • Formula:C24H29F2N4O2P
  • Molecular Weight:474.48

IUPAC Name: (R)-1-(4-((1-(3-amino-5-(difluoromethyl)phenyl)ethyl)amino)-7-methoxy-2-methylquinazolin-6-yl)phosphinane 1-oxide

InChIKey: AYUPAZPTYFGDHL-CQSZACIVSA-N

SMILES: COC1=CC2=NC(C)=NC(N[C@H](C)C3=CC(N)=CC(C(F)F)=C3)=C2C=C1P4(CCCCC4)=O

Biological Activity: SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].

Cat. No. Product Name Purity Description Pricing
HY-145047
SOS1-IN-4 SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References