2740453-91-0
2740453-91-0
Chemical Structure
Methyltetrazine-SS-NHS
- CAS No.: 2740453-91-0
- Formula:C20H22N6O5S2
- Molecular Weight:490.56
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 3-((3-((4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)amino)-3-oxopropyl)disulfanyl)propanoate
InChIKey: SFIAJZGJDUJUCL-UHFFFAOYSA-N
SMILES: CC1=NN=C(C2=CC=C(CNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)C=C2)N=N1
Biological Activity: Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Methyltetrazine-SS-NHS | Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. | |||||||||||||||||||||
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