2747996-65-0
2747996-65-0
Chemical Structure
rel-A-395 hydrochloride
- CAS No.: 2747996-65-0
- Formula:C26H36ClFN4O2S
- Molecular Weight:523.11
InChIKey: JUZXQLNCGDDSMJ-NNEMXYTISA-N
SMILES: O=S(N1CCN(C2=CC=C([C@H]3CN(C4C(C(F)=CC=C5)=C5CC4)C[C@@H]3N(C)C)C=C2)CC1)(C)=O.Cl
Biological Activity: rel-A-395 hydrochloride is the relative configuration of A-395 (HY-101512) hydrochloride. A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM[1].
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rel-A-395 hydrochloride | rel-A-395 hydrochloride is the relative configuration of A-395 (HY-101512) hydrochloride. A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. | |||||||||||||||||||||
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