2748304-41-6
2748304-41-6
Chemical Structure
EDMA hydrochloride
- CAS No.: 2748304-41-6
- Formula:C12H18ClNO2
- Molecular Weight:243.73
InChIKey: OLGSWAGTAZJFDI-UHFFFAOYSA-N
SMILES: CC(CC1=CC2=C(C=C1)OCCO2)NC.Cl
Biological Activity: EDMA hydrochloride is a derivative of MDMA. EDMA hydrochloride is a substrate for multiple neurotransmitter transporters, including serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET). EDMA hydrochloride has 5-HT releasing activity at SERT (EC50 = 117 nM) and MPP+ releasing activity at DAT (EC50 = 597 nM) and NET (EC50 = 325 nM)[1].
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EDMA hydrochloride | EDMA hydrochloride is a derivative of MDMA. EDMA hydrochloride is a substrate for multiple neurotransmitter transporters, including serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET). EDMA hydrochloride has 5-HT releasing activity at SERT (EC50 = 117 nM) and MPP+ releasing activity at DAT (EC50 = 597 nM) and NET (EC50 = 325 nM). | |||||||||||||||||||||
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References
- [1]. Del Bello F, et al. Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine. Bioorg Med Chem. 2015 Sep 1;23(17):5574-9. [Content Brief]
