2750413-99-9
2750413-99-9
Chemical Structure
CCG-273463
- CAS No.: 2750413-99-9
- Formula:C26H25BrN4O3
- Molecular Weight:521.41
IUPAC Name: (R,Z)-3-((4-(2-bromoacetamido)-3,5-dimethyl-1H-pyrrol-2-yl)methylene)-2-oxo-N-(1-phenylethyl)indoline-5-carboxamide
InChIKey: XCZKXWQNBNADHK-GEYIUBJWSA-N
SMILES: O=C1NC2=CC=C(C=C2/C1=C/C3=C(C(NC(CBr)=O)=C(N3)C)C)C(N[C@H](C)C4=CC=CC=C4)=O
Biological Activity: CCG-273463 is a potent, selective and covalent GRK5 inhibitor with an IC50 value of 8.6 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, and cancer[1].
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CCG-273463 | CCG-273463 is a potent, selective and covalent GRK5 inhibitor with an IC50 value of 8.6 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, and cancer. | |||||||||||||||||||||
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