2750707-05-0
2750707-05-0
Chemical Structure
MRIA9
- CAS No.: 2750707-05-0
- Formula:C24H22ClFN6O3
- Molecular Weight:496.92
IUPAC Name: 8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(3-fluoropyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: QKNBRNSGPNCARD-SGNKCFNYSA-N
SMILES: N[C@@H](CO1)CO[C@H]1CN(C2=O)C3=NC(NC)=NC=C3C=C2C4=CC=C(C=C4Cl)C5=NC=CC=C5F
Biological Activity: MRIA9, a chemical probe, is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MRIA9 | 98.88% | MRIA9, a chemical probe, is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively. | ||||||||||||||||||||
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